Pharmacologic effect of angel's trumpet (Brugmansia suaveolens) extract in cats (Felis domesticus) Nathaniel R. Mendoza. by Nathaniel R. Mendoza.

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Indang, Cavite : 2007. Cavite State University- Main Campus,Description: xiv, 52 pages : 28 cm. illustrationsContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
Subject(s): DDC classification:
  • 636.8  M52 2007
Online resources: Production credits:
  • College of Veterinary Medicine and Biomedical Sciences (VETMET)
Abstract: MENDOZA, NATHANIEL REALEZA, "PHARMACOLOGIC EFFECT OF ANGEL'S TRUMPET (Brugmansia suaveolens) EXTRACT IN CATS (Fells domesticus)" Undergraduate Thesis. Doctor of Veterinary Medicine, Cavite State University, Indang, Cavite, April 2007. Adviser. Eugene M. Principe, DVM, MS. The study evaluated the effect of angel's trumpet extract on the vital signs and withdrawal reflex, other untoward reactions were noted. The study used six apparently healthy cats that were blocked into pairs. Each pair received a different treatments per week. The treatments were: Treatment 1: dilution 1 (500 grams of leaves into 250 ml. of distilled water), Treatment 2: dilution 2 (250 grams of leaves into 500 ml. of distilled water) and Treatment 3: sterile water. Mean of heart rate, respiratory rate and rectal temperature have no significant differences in between treatments except for the mean heart rate at five minutes after administration. There was significant increase in heart rate mean at treatment 1 and treatment 2 compared to treatment 3. Within treatments, treatment 1 and treatment 3 showed no significant differences in different time interval. In treatment 2, highly significant increased of mean heart rate was observed on five, 10 and 15 minutes compared to baseline. Analgesic effects of the treatments were also assessed by using pinch test. Two animals showed no withdrawal response in treatment 1, first one, "analgesia" start at 16 minutes and end at 24 minutes while the other one, "analgesia" start at eight minutes and end in 24 minutes after administration of extract. In treatment 2, one animal showed no withdrawal response which starts at eight minutes and end in 24 minutes. In treatment 3, withdrawal response was observed in all animals. The observed analgesia was not true analgesia but was attributed to muscle relaxation that modified the withdrawal reflex reaction at pinch test. Untoward reaction was seen on treatment 1 and treatment 2. Animals given by angel's trumpet extract shows dilation of pupil, vocalization and hyperactivity.
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Theses / Manuscripts Theses / Manuscripts Ladislao N. Diwa Memorial Library Theses Section Non-fiction 636.8 M52 2007 (Browse shelf(Opens below)) Link to resource Room use only T-3459 00007317

Thesis (Doctor of Veterinary Medicine) Cavite State University.

Includes bibliographical references.

College of Veterinary Medicine and Biomedical Sciences (VETMET)

MENDOZA, NATHANIEL REALEZA, "PHARMACOLOGIC EFFECT OF ANGEL'S TRUMPET (Brugmansia suaveolens) EXTRACT IN CATS (Fells domesticus)" Undergraduate Thesis. Doctor of Veterinary Medicine, Cavite State University, Indang, Cavite, April 2007. Adviser. Eugene M. Principe, DVM, MS.
The study evaluated the effect of angel's trumpet extract on the vital signs and withdrawal reflex, other untoward reactions were noted. The study used six apparently healthy cats that were blocked into pairs. Each pair received a different treatments per week. The treatments were: Treatment 1: dilution 1 (500 grams of leaves into 250 ml. of distilled water), Treatment 2: dilution 2 (250 grams of leaves into 500 ml. of distilled water) and Treatment 3: sterile water. Mean of heart rate, respiratory rate and rectal temperature have no significant differences in between treatments except for the mean heart rate at five minutes after administration. There was significant increase in heart rate mean at treatment 1 and treatment 2 compared to treatment 3. Within treatments, treatment 1 and treatment 3 showed no significant differences in different time interval. In treatment 2, highly significant increased of mean heart rate was observed on five, 10 and 15 minutes compared to baseline. Analgesic effects of the treatments were also assessed by using pinch test. Two animals showed no withdrawal response in treatment 1, first one, "analgesia" start at 16 minutes and end at 24 minutes while the other one, "analgesia" start at eight minutes and end in 24 minutes after administration of extract. In treatment 2, one animal showed no withdrawal response which starts at eight minutes and end in 24 minutes. In treatment 3, withdrawal response was observed in all animals. The observed analgesia was not true analgesia but was attributed to muscle relaxation that modified the withdrawal reflex reaction at pinch test. Untoward reaction was seen on treatment 1 and treatment 2. Animals given by angel's trumpet extract shows dilation of pupil, vocalization and hyperactivity.

Submitted to the University Library 03-30-2007 T-3459

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