000			03151nam a22003137a 4500
003			OSt
005			20220418163909.0
008			211128b |||||||| |||| 00| 0 eng d
020			_a9789386391261 (hardcover)
040			_cCvSU Main Campus Library _erda
041			_aeng
050			_aRS403 _bK96 2018
100			_914858 _aKumar, Dheeraj _eauthor
245			_aMedicinal chemistry and drug discovery / _cDheeraj Kumar.
260			_aNew Delhi, India : _b Random Publications, _c2018
300			_a256 pages : _billustrations ; _c24 cm
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes bibliographical references and index.
505			_aGeneral properties of enzymes -- Medicinal chemistry -- The basis of pharmacokinetics -- Computer pharmacy and drug discovery -- Act and rules of drug and cosmetic -- Anti-diabetic drug -- Mechanisms of drug action and resistance.
520			_a"In particular, medicinal chemistry in its most common practice – focusing on small organic molecules – encompasses synthetic organic chemistry and aspects of natural products and computational chemistry in close combination with chemical biology, enzymology and structural biology, together aiming at the discovery and development of new therapeutic agents. Practically speaking, it involves chemical aspects of identification, and then systematic, thorough synthetic alteration of new chemical entities to make them suitable for therapeutic use. It includes synthetic and computational aspects of the study of existing drugs and agents in development in relation to their bioactivities (biological activities and properties), i.e., understanding their structure-activity relationships (SAR). Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for purpose of medicinal products. This book aims to be a reference book for the Undergraduate students of Pharmacy. The book provides a comprehensive, balanced introduction and detailed information on the various classes of drugs used in Pharmacy. The approach to medicinal chemistry is kept as simple as possible. It includes mechanism of action, structure activity relationships and mainly focus on the synthesis of selected compounds as per the course curriculum. Special historical perspectives on drug development help to provide an understanding of what medicinal chemistry is and how this science is used to develop new therapeutic agents. This book will be of interest to instructors and students of pharmacy, pharmacology, medicinal chemistry and biochemistry and to medicinal chemist pharmaceutical scientists’ molecular biologists and biochemists."--Back cover
541			_aFund 164 _bBookQuick Marketing _cPurchased _d10/31/2019 _e78088 _fNEJ _hPHP 6,295.50 _p2019-10-818 _q2019-1-0678
650		0	_914859 _aPharmaceutical chemistry
650		0	_914860 _aEnzymes
650		0	_914861 _aPharmacokinetics
856			_uhttp://library.cvsu.edu.ph/cgi-bin/koha/opac-retrieve-file.pl?id=c42e82974607683aeea7028a38b79e34 _yClick here to view the table of contents
942			_2lcc _cBK
999			_c34932 _d34932