MARC details
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04720nam a2200313 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20231120101913.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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170503s19uu xx 00 eng d |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CvSU Main Campus Library |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
634 |
| Item number |
C88 2015 |
| 100 #0 - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Crystal, Joven C. |
| 9 (RLIN) |
15534 |
| Relator term |
author |
| 245 10 - TITLE STATEMENT |
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| Title |
Hypoglycemic activity of mabolo (Diospyros discolor Willd.) fruit extract in alloxan-induced diabetic male albino mice / |
| Statement of responsibility, etc. |
by Joven C. Crystal. |
| 260 0# - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Indang, Cavite : |
| Date of publication, distribution, etc. |
2015. |
| Name of publisher, distributor, etc. |
Cavite State University- Main Campus, |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xiii, 62 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
28 cm. |
| 336 ## - CONTENT TYPE |
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| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
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| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
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| Source |
rdacarrier |
| Carrier type term |
volume |
| 500 ## - GENERAL NOTE |
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| General note |
Thesis (Bachelor of Science in Biology) Cavite State University |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographical references. |
| 508 ## - CREATION/PRODUCTION CREDITS NOTE |
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| College and Department |
College of Arts and Sciences (CAS), Department of Biological Sciences. |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
ABSTRACT<br/>JOVEN C. CRYSTAL. Hypoglycemic Activity of Mabolo (Diospyros discolor Wild.) Fruit Extract in Alloxan-Induced Diabetic Male Albino Mice. Undergraduate Thesis. Department of Biological Sciences, College of Arts and Sciences, Cavite State University, Indang, Cavite. April 2015. Adviser: Dr. Rosemarie R. Calma. <br/>Diospyros discolor Willd locally known as "mabolo" is popular because of its wood and leaves used for ornamental and folk medicine purposes, respectively. This study aimed to evaluate the hypoglycemic effect of the different treatment concentrations of D. Discolor Willd fruit aqueous extract on alloxan-induced acute diabetes in male albino mice. Specifically, it aimed to: compare the fasting blood sugar levels of alloxan- induced diabetic mice treated with different concentrations of aqueous D. Discolor Willd fruit extract prepared by infusion or dichloromethane (DCM) extraction; quantify the percentage reduction in fasting blood sugar level of the different treatment groups; determine which of the D. Discolor Willd. aqueous fruit extracts is effectively hypoglycemic; describe the histological sections of the pancreas of the male albino mice treated with D. Discolor Willd. fruit extracts: and quantify the effect of the different treatment concentrations and aqueous D. discolor Willd. fruit extracts on the Islets of Langerhans. <br/>This study was conducted from September 2014 to February 2015 at the Department of Biological Sciences Laboratory, College of Arts and Sciences, Cavite State University Main Campus, Indang, Cavite. The aqueous (AQE) and Dichloromethane (DCME) extracts of D. discolor (Willd.) fruit were evaluated for hypoglycemic activity in alloxan-induced diabetic male albino mice. Repeated two-way ANOVA showed the FBS levels and percentage reductions of the treatment groups was significantly different from the controls. Post hoc Bonferroni During the 1st hour, AQE500 is significantly lower than the GS (p < 0.001) unlike DCME500 (p < 0.001) and DCME1000 that were significantly higher than the GS. On the 4th hour, only the mean FBS level of AQE1000 is significantly lower than the GS (p.< 0.001. And lastly, on the 10th hour, only the AQE1000 is significantly lower (p < 0.01) and DCME500 is significantly higher (p < 0.001) than GS. The hours of induction and the treatment concentration significantly affect the mean FBS levels of the alloxan- induced diabetic mice. The AQE 1000 has significantly low FBS levels during the 4th and 10th hour. The percent FBS reduction of the different treatments were compared with the GS. <br/>The FBS levels and percentage reductions of the treatment groups were significantly different from the GS control. AQE at 1000mg/kg BW significantly reduced the fasting blood sugar (FBS) level during the 4th and 10th hour of diabetic induction while it is only effective on the 10th hour on DCME at 500 mg/kg BW compared with the Glimepiride solosa (GS). Hence, among the different concentrations of Diospyros discolor Willd, the AQE1000 is the most effective hypoglycemic treatment. Only nucleated acinar cells were observed. Other histopathological signs were not detected in the controls nor in the treatment groups. These findings may indicate that the expected histopathological changes did not manifest since induction of mild diabetes was short-term resulting in acute toxicity. <br/> |
| 541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE |
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| Method of acquisition |
Submitted to the University Library |
| Date of acquisition |
02/14/2017 |
| Accession number |
T-6167 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Mabolo |
| 9 (RLIN) |
3401 |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) |
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| 9 (RLIN) |
1672 |
| Course or Program |
Bachelor of Science in Biology |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Calma, Rosemarie R. |
| 9 (RLIN) |
17480 |
| Relator term |
adviser |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| Electronic File |
<a href="http://library.cvsu.edu.ph/cgi-bin/koha/opac-retrieve-file.pl?id=8de302e73743e4f2f6d88d34747c6483">http://library.cvsu.edu.ph/cgi-bin/koha/opac-retrieve-file.pl?id=8de302e73743e4f2f6d88d34747c6483</a> |
| Link text |
Click here to view thesis abstract and table of contents |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Theses / Manuscripts |
