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Medicinal chemistry and drug discovery / Dheeraj Kumar.

By: Material type: TextTextLanguage: English Publication details: New Delhi, India : Random Publications, 2018Description: 256 pages : illustrations ; 24 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
ISBN:
  • 9789386391261 (hardcover)
Subject(s): LOC classification:
  • RS403 K96 2018
Online resources:
Contents:
General properties of enzymes -- Medicinal chemistry -- The basis of pharmacokinetics -- Computer pharmacy and drug discovery -- Act and rules of drug and cosmetic -- Anti-diabetic drug -- Mechanisms of drug action and resistance.
Summary: "In particular, medicinal chemistry in its most common practice – focusing on small organic molecules – encompasses synthetic organic chemistry and aspects of natural products and computational chemistry in close combination with chemical biology, enzymology and structural biology, together aiming at the discovery and development of new therapeutic agents. Practically speaking, it involves chemical aspects of identification, and then systematic, thorough synthetic alteration of new chemical entities to make them suitable for therapeutic use. It includes synthetic and computational aspects of the study of existing drugs and agents in development in relation to their bioactivities (biological activities and properties), i.e., understanding their structure-activity relationships (SAR). Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for purpose of medicinal products. This book aims to be a reference book for the Undergraduate students of Pharmacy. The book provides a comprehensive, balanced introduction and detailed information on the various classes of drugs used in Pharmacy. The approach to medicinal chemistry is kept as simple as possible. It includes mechanism of action, structure activity relationships and mainly focus on the synthesis of selected compounds as per the course curriculum. Special historical perspectives on drug development help to provide an understanding of what medicinal chemistry is and how this science is used to develop new therapeutic agents. This book will be of interest to instructors and students of pharmacy, pharmacology, medicinal chemistry and biochemistry and to medicinal chemist pharmaceutical scientists’ molecular biologists and biochemists."--Back cover
List(s) this item appears in: Print Books 2022
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Holdings
Item type Current library Collection Call number Materials specified Status Notes Date due Barcode
Books Books Ladislao N. Diwa Memorial Library Reserve Section Non-fiction RUS RS403 K96 2018 (Browse shelf(Opens below)) Room use only 78088 00079035

Includes bibliographical references and index.

General properties of enzymes -- Medicinal chemistry -- The basis of pharmacokinetics -- Computer pharmacy and drug discovery
-- Act and rules of drug and cosmetic -- Anti-diabetic drug -- Mechanisms of drug action and resistance.

"In particular, medicinal chemistry in its most common practice – focusing on small organic molecules – encompasses synthetic organic chemistry and aspects of natural products and computational chemistry in close combination with chemical biology, enzymology and structural biology, together aiming at the discovery and development of new therapeutic agents. Practically speaking, it involves chemical aspects of identification, and then systematic, thorough synthetic alteration of new chemical entities to make them suitable for therapeutic use. It includes synthetic and computational aspects of the study of existing drugs and agents in development in relation to their bioactivities (biological activities and properties), i.e., understanding their structure-activity relationships (SAR). Pharmaceutical chemistry is focused on quality aspects of medicines and aims to assure fitness for purpose of medicinal products. This book aims to be a reference book for the Undergraduate students of Pharmacy. The book provides a comprehensive, balanced introduction and detailed information on the various classes of drugs used in Pharmacy. The approach to medicinal chemistry is kept as simple as possible. It includes mechanism of action, structure activity relationships and mainly focus on the synthesis of selected compounds as per the course curriculum. Special historical perspectives on drug development help to provide an understanding of what medicinal chemistry is and how this science is used to develop new therapeutic agents. This book will be of interest to instructors and students of pharmacy, pharmacology, medicinal chemistry and biochemistry and to medicinal chemist pharmaceutical scientists’ molecular biologists and biochemists."--Back cover

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