Serological evaluation of the rabies antibody titers of veterinarians in Cavite / by Joshua Nico R. Dilig.

By:

Dilig, Joshua Nico R [author]

Contributor(s):

Talactac, Melbourne R [adviser]

Material type: Text

TextLanguage: English Publication details: Indang, Cavite, Cavite State University- Main Campus, 2022.Description: x, 50 pages : illustrations ; 28 cmContent type:

text

Media type:

unmediated

Carrier type:

volume

Subject(s):

DDC classification:

616.9 D57 2022

Online resources:

Click here to view the Abstract and Table of Contents

Production credits:

College of Veterinary Medicine and Biomedical Sciences (CVMBS)

Abstract: Rabies continue to be a public health problem in the Philippines, it is one of the top 10 countries with rabies problem and is responsible for the deaths of 200 to 300 Filipinos per year. The purposed of the study is to detect, evaluate, and quantify the rabies neutralizing antibody titer through the rapid fluorescent focus inhibition test (RFFIT) using the sera of 63 selected small animal practitioner veterinarians in the province of Cavite who voluntarily participated in the study. This study is a descriptive type of research, aside from blood collection, a structured questionnaire was provided and filled by each (63) of the respondents to describe the characteristic of the variables under study that may affect the level of serum rabies neutralizing antibody titer from the study population. From the questionnaire survey, majority of the respondents were female (73%) and only 27% were male respondents. Majority are at the age of 31 to 40 years old (47.62%) but there were 51 to 60 years old (3.17%) who participated in the study. Most of the respondents have been a small animal veterinary practitioner for 1 to 3 years (34.92%). Based on the estimated average number of cats and dogs handled per day, majority of them answered that they handled 3 to 6 cats (42.86%) and more than 10 dogs (52.38%) per day. two milliliters of blood were collected from the medial cubital vein of the 63 respondents by a registered medical technologist following humane protocol and centrifuged. The sera are then separated into a microtainer with labelled identification number of the respondents. Sample (sera) processing and titration of antibodies were conducted at the Research Institute for Tropical Medicine (RITM). The reference values for rabies neutralizing antibody titers used in the study were based on the World Health Organization or WHO (>0.5 IU/ml). Based on the reference value (>0.5 IU/ml) of the WHO, the result of the study showed that majority of the respondents with a total number of 62 or 98.41% out of the total sample size (63) had rabies virus antibody titers greater than or equal to 0.5 IU/ml which is an adequate response to rabies vaccination according to the World Health Organization. Only 1 or 1.59% of the respondent had rabies virus antibody titers lower than 0.5 IU/ml which is an inadequate immune response, and a booster dose of rabies vaccine may be recommended.

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Holdings
Item type	Current library	Collection	Call number	Materials specified	URL	Status	Notes	Date due	Barcode
Theses / Manuscripts	Ladislao N. Diwa Memorial Library Theses Section	Non-fiction	616.9 D57 2022 (Browse shelf(Opens below))		Link to resource	Room use only	T-9246		00083623

Thesis (Doctor of Veterinary Medicine) Cavite State University.

Includes bibliographical references.

College of Veterinary Medicine and Biomedical Sciences (CVMBS)

Rabies continue to be a public health problem in the Philippines, it is one of the top 10 countries with rabies problem and is responsible for the deaths of 200 to 300 Filipinos per year. The purposed of the study is to detect, evaluate, and quantify the rabies neutralizing antibody titer through the rapid fluorescent focus inhibition test (RFFIT) using the sera of 63 selected small animal practitioner veterinarians in the province of Cavite who voluntarily participated in the study. This study is a descriptive type of research, aside from blood collection, a structured questionnaire was provided and filled by each (63) of the respondents to describe the characteristic of the variables under study that may affect the level of serum rabies neutralizing antibody titer from the study population. From the questionnaire survey, majority of the respondents were female (73%) and only 27% were male respondents. Majority are at the age of 31 to 40 years old (47.62%) but there were 51 to 60 years old (3.17%) who participated in the study. Most of the respondents have been a small animal veterinary practitioner for 1 to 3 years (34.92%). Based on the estimated average number of cats and dogs handled per day, majority of them answered that they handled 3 to 6 cats (42.86%) and more than 10 dogs (52.38%) per day. two milliliters of blood were collected from the medial cubital vein of the 63 respondents by a registered medical technologist following humane protocol and centrifuged. The sera are then separated into a microtainer with labelled identification number of the respondents. Sample (sera) processing and titration of antibodies were conducted at the Research Institute for Tropical Medicine (RITM). The reference values for rabies neutralizing antibody titers used in the study were based on the World Health Organization or WHO (>0.5 IU/ml). Based on the reference value (>0.5 IU/ml) of the WHO, the result of the study showed that majority of the respondents with a total number of 62 or 98.41% out of the total sample size (63) had rabies virus antibody titers greater than or equal to 0.5 IU/ml which is an adequate response to rabies vaccination according to the World Health Organization. Only 1 or 1.59% of the respondent had rabies virus antibody titers lower than 0.5 IU/ml which is an inadequate immune response, and a booster dose of rabies vaccine may be recommended.

Submitted to the University Library 07/12/2022 T-9246

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