The effect of D-Cloprostenol (Veteglan) and dinopost tromethamine (Lutalyse) on the parturition of sows / by Katrina Claudia D. Escuril.

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Indang, Cavite : Cavite State University- Main Campus, 2009.Description: xiii, 50 pages : illustrations ; 28 cmContent type:
  • text
Media type:
  • unmediated
Carrier type:
  • volume
Subject(s): DDC classification:
  • 636.4  Es1 2009
Online resources: Production credits:
  • College of Veterinary Medicine and Biomedical Sciences (VETMET)
Abstract: ESCURIL, 'KATRINA CLAUDIA R. "THE EFFECT OF D-CLOPROSTENOL (VETEGLAN®) AND DINOPROST TROMETHAMINE (LUTALYSE®) ON THE PARTURITION OF SOWS." Doctor of veterinary Medicine. Cavite State University, Indang, Cavite. March 2009. Adviser: Dr. Eugene M. Principe, DVM. The study was conducted to determine and compare the effect of d-cloprostenol (Veteglan°), a synthetic analogue of Prostaglandin Fla and dinoprost tromethamine (Lutalyse), a natural form of Prostaglandin Fax, on the parturition of sows. The study utilized 30 sows which were randomly distributed to three treatments through a completely randomized design (CRD). The three treatments were: (1) 1 ml. saline IM (control); (2) 175 micrograms Veteglae IM and (3 ) 5 mg Lutalyse® IM. Treatment 1 and 2 were both given on the 113th day of gestation and on the 111th day of gestation for treatment 3. The mean (± SD) interval (hr) from injection until birth of the three treatments were: 60.31 (± 3)9), 23:29 (± 5.50) and 66.23 (± 66.11) respectively. Mean (± SD) interval (min) between piglets were: 25.30 (± 16.00), 24.30 (± 10.44) and 29.18 (± 7.32) respectively. Time from last piglet to placental expulsion (hi) were : 7.53 (± 4.30), 9.55 (± 5.49) and 11.04 (± 7.13) respectively. And lastly, 11.10 (± 3.44), 13.22 (± 5.46) and 15.18 (± 7.02) respectively for the duration of farrowing. The mean induction interval, mean interval between successive piglets and mean interval from last piglet to placental expulsion was significantly shorter in sows ()riven d — cloprostenol when compared to that in sows given dinoprost tromethamine. However, the difference was not significant for the farrowing duration. Out of 10 sows, 1 sow treated with d-cloprostenol farrowed within 20 hrs after injection while the remaining 9 sows farrowed until 31 hr after injection. However, 7 out of 10 sows treated with dinoprost tromethamine farrowed 30hrs post injection while the remaining 3 sows failed to respond. For both d-cloprostenol and dinoprost tromethamine, there was no significant difference on the occurrence of stillbirth. With shorter induction interval and interval between successive, higher percent of sows farrowing as expected and cheaper cost per dose, the use of d-cloprostenol showed to be more economical.
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Theses / Manuscripts Theses / Manuscripts Ladislao N. Diwa Memorial Library Theses Section Non-fiction 636.4 Es1 2009 (Browse shelf(Opens below)) Link to resource Room use only T-3937 00007813

Thesis (Doctor of Veterinary Medicine) Cavite State University

Includes bibliographical references.

College of Veterinary Medicine and Biomedical Sciences (VETMET)

ESCURIL, 'KATRINA CLAUDIA R. "THE EFFECT OF D-CLOPROSTENOL (VETEGLAN®) AND DINOPROST TROMETHAMINE (LUTALYSE®) ON THE PARTURITION OF SOWS." Doctor of veterinary Medicine. Cavite State University, Indang, Cavite. March 2009. Adviser: Dr. Eugene M. Principe, DVM.

The study was conducted to determine and compare the effect of d-cloprostenol (Veteglan°), a synthetic analogue of Prostaglandin Fla and dinoprost tromethamine (Lutalyse), a natural form of Prostaglandin Fax, on the parturition of sows. The study utilized 30 sows which were randomly distributed to three treatments through a completely randomized design (CRD). The three treatments were: (1) 1 ml. saline IM (control); (2) 175 micrograms Veteglae IM and (3 ) 5 mg Lutalyse® IM. Treatment 1 and 2 were both given on the 113th day of gestation and on the 111th day of gestation for treatment 3.

The mean (± SD) interval (hr) from injection until birth of the three treatments were: 60.31 (± 3)9), 23:29 (± 5.50) and 66.23 (± 66.11) respectively. Mean (± SD) interval (min) between piglets were: 25.30 (± 16.00), 24.30 (± 10.44) and 29.18 (± 7.32) respectively. Time from last piglet to placental expulsion (hi) were : 7.53 (± 4.30), 9.55 (± 5.49) and 11.04 (± 7.13) respectively. And lastly, 11.10 (± 3.44), 13.22 (± 5.46) and 15.18 (± 7.02) respectively for the duration of farrowing. The mean induction interval, mean interval between successive piglets and mean interval from last piglet to placental expulsion was significantly shorter in sows ()riven d — cloprostenol when compared to that in sows given dinoprost tromethamine. However, the difference was not significant for the farrowing duration. Out of 10 sows, 1 sow treated with d-cloprostenol farrowed within 20 hrs after injection while the remaining 9 sows farrowed until 31 hr after injection.

However, 7 out of 10 sows treated with dinoprost tromethamine farrowed 30hrs post injection while the remaining 3 sows failed to respond. For both d-cloprostenol and dinoprost tromethamine, there was no significant difference on the occurrence of stillbirth. With shorter induction interval and interval between successive, higher percent of sows farrowing as expected and cheaper cost per dose, the use of d-cloprostenol showed to be more economical.

Submitted to the University Library 05/05/2009 T-3937

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