MARC details
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03813nam a2200325 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20230813092147.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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220622b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CvSU Main Campus Library |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
eng |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
581.634 |
| Item number |
C82 2019 |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| 9 (RLIN) |
25151 |
| Personal name |
Costa, Christian Joshua S. |
| Relator term |
author |
| 245 10 - TITLE STATEMENT |
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| Title |
Phytochemical analysis and evaluation of cytotoxicity and genotoxicity of breynia androgyna L. (Binahian) leaf extract / |
| Statement of responsibility, etc. |
by Christian Joshua S. Costa. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Indang, Cavite : |
| Name of publisher, distributor, etc. |
Cavite State University- Main Campus, |
| Date of publication, distribution, etc. |
2019. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xiv, 87 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
28 cm. |
| 336 ## - CONTENT TYPE |
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| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
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| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
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| Source |
rdacarrier |
| Carrier type term |
volume |
| 500 ## - GENERAL NOTE |
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| General note |
Thesis (Bachelor of Science in Biology Major in General Biology) Cavite State University. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographical references. |
| 508 ## - CREATION/PRODUCTION CREDITS NOTE |
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| College and Department |
College of Arts and Sciences (CAS), Department of Biological Sciences |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
COSTA, CHRISTIAN JOSHUA S. Phytochemical Analysis and Evaluation of<br/>Cytotoxicity and Genotoxicity of Breynia androgyna L. (Binahian) Leaf Extract.<br/>Undergraduate Thesis. Bachelor of Science in Biology major in General Biology. Cavite<br/>State University, Indang, Cavite. June 2019. Adviser: Ms. Liwayway P. Taglinao.<br/><br/>A study was conducted to assess the cytotoxicity and genotoxicity of Breynia androgyna<br/>L. (Binahian) ethanolic leaf extract using Allium cepa L. (Onion) test. Phytochemical analysis<br/>was performed on the leaf ethanolic extract of B. androgyna plant. In accordance, B. androgyna<br/>extract was diluted into different concentrations of plant extract as the treatment groups together<br/>with control groups. Six groups of onion bulbs were submerged into different treatment groups<br/>for two days and the morphological effects of the treatment were observed and documented.<br/>Onion roots were harvested and fixed for microscopic observation of the mitotic index and<br/>chromosomal aberrations.<br/><br/>This study showed that the phytochemical compounds that were present on the B.<br/>adrogyna consist of tannins, flavonoids, phenolics, alkaloids and steroids. There is a significant<br/>difference on the onion root length when submerged to B. androgyna extract in comparison with<br/>the negative control group (p<0.05). Thus, there is a significant inhibition of mitotic activity in the<br/>onion group treated with plant extract compared to the negative control (p<0.05). On the other<br/>hand, the inhibition of the mitotic activity was highly significant in the 750 ug/mL and 1000<br/>gg/mL B. androgyna plant extract. One thousand gg/mL B. androgyna plant extract decreases<br/>mitotic index at 32% thus signifying it as having sublethal effects on an organism. The number<br/>of chromosomal aberrations increases as the level of concentration of plant extract increases<br/>compared to the negative control (tapwater). There was statistically significant differences at all<br/>the values except for 250 pg/ml B. androgyna extract concentration and 500 gg/mL<br/>B.androgyna extract concentration (p<0.05).Hence, the leaves of B. androgyna are commonly<br/>utilized by human as food or medicine as revealed by the survey. However, B. androgyna plant<br/>leaves, if consumed or applied at certain doses (approximately beyond 500 gg/mL), will induce<br/>a cytotoxic and genotoxic effect on an organism |
| 541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE |
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| Method of acquisition |
Submitted to the University Library |
| Date of acquisition |
July 09, 2019 |
| Accession number |
T-8264 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
25152 |
| Topical term or geographic name entry element |
Leaf extract |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| 9 (RLIN) |
3450 |
| Topical term or geographic name entry element |
Plants |
| General subdivision |
Medicinal |
| 690 ## - LOCAL SUBJECT ADDED ENTRY--TOPICAL TERM (OCLC, RLIN) |
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| 9 (RLIN) |
1672 |
| Course or Program |
Bachelor of Science in Biology |
| Major |
General Biology |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Taglinao, Liwayway P. |
| Relator term |
adviser |
| 9 (RLIN) |
19889 |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| Electronic File |
<a href="http://library.cvsu.edu.ph/cgi-bin/koha/opac-retrieve-file.pl?id=1b6c42c3736811c893f231f6b03f628c">http://library.cvsu.edu.ph/cgi-bin/koha/opac-retrieve-file.pl?id=1b6c42c3736811c893f231f6b03f628c</a> |
| Link text |
Click here to view abstract and table of contents |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Koha item type |
Theses / Manuscripts |
